Rabbit Anti-PHPT1 Recombinant Antibody (001) (CBMAB-P1712-YC)

Name: Rabbit Anti-PHPT1 Recombinant Antibody (001)
SKU: CBMAB-P1712-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

001

Application

IHC, ICC, IF

Immunogen

Recombinant human PHPT1 protein

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Phosphohistidine Phosphatase 1

Introduction

PHPT1 is an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels.

Entrez Gene ID

29085

UniProt ID

Q9NRX4

Alternative Names

Phosphohistidine Phosphatase 1; Sex-Regulated Protein Janus-A; Protein Histidine Phosphatase; Protein Janus-A Homolog; PHP14; PHP; Epididymis Secretory Sperm Binding Protein Li 132P; 14 KDa Phosphohistidine Phosphatase;

Function

Exhibits phosphohistidine phosphatase activity.

Biological Process

Negative regulation of ATP citrate synthase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of lyase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of T cell receptor signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Peptidyl-histidine dephosphorylationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of cell motilityManual Assertion Based On ExperimentIMP:BHF-UCL
Protein dephosphorylationManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of actin cytoskeleton reorganizationManual Assertion Based On ExperimentIMP:BHF-UCL

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Human Recombinant PHPT1 protein, His Tag (CAT#: V2LY-0526-LY6149)

Mouse Anti-PHPT1 Recombinant Antibody (C-6) (CAT#: CBMAB-P1713-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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