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Rabbit Anti-PHPT1 Recombinant Antibody (001) (CBMAB-P1712-YC)

Provided herein is a Rabbit monoclonal antibody against Human Phosphohistidine Phosphatase 1. The antibody can be used for immunoassay techniques, such as IHC, ICC, IF.
See all PHPT1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
001
Antibody Isotype
IgG
Application
IHC, ICC, IF

Basic Information

Immunogen
Recombinant human PHPT1 protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Phosphohistidine Phosphatase 1
Introduction
PHPT1 is an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels.
Entrez Gene ID
UniProt ID
Alternative Names
Phosphohistidine Phosphatase 1; Sex-Regulated Protein Janus-A; Protein Histidine Phosphatase; Protein Janus-A Homolog; PHP14; PHP; Epididymis Secretory Sperm Binding Protein Li 132P; 14 KDa Phosphohistidine Phosphatase;
Function
Exhibits phosphohistidine phosphatase activity.
Biological Process
Negative regulation of ATP citrate synthase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of lyase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of T cell receptor signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Peptidyl-histidine dephosphorylationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of cell motilityManual Assertion Based On ExperimentIMP:BHF-UCL
Protein dephosphorylationManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of actin cytoskeleton reorganizationManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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