Mouse Anti-PHPT1 Recombinant Antibody (C-6) (CBMAB-P1713-YC)

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Basic Information

Host Animal
Mouse
Clone
C-6
Application
WB, IP, IF, ELISA
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Phosphohistidine Phosphatase 1
Introduction
PHPT1 is an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels.
Entrez Gene ID
Human29085
Mouse75454
Rat296571
UniProt ID
HumanQ9NRX4
MouseQ9DAK9
RatD3ZP47
Alternative Names
Phosphohistidine Phosphatase 1; Sex-Regulated Protein Janus-A; Protein Histidine Phosphatase; Protein Janus-A Homolog; PHP14; PHP; Epididymis Secretory Sperm Binding Protein Li 132P; 14 KDa Phosphohistidine Phosphatase;
Function
Exhibits phosphohistidine phosphatase activity.
Biological Process
Negative regulation of ATP citrate synthase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of lyase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of T cell receptor signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Peptidyl-histidine dephosphorylationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of cell motilityManual Assertion Based On ExperimentIMP:BHF-UCL
Protein dephosphorylationManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of actin cytoskeleton reorganizationManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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