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Mouse Anti-PKP3 Recombinant Antibody (12B11F8) (CBMAB-P1971-YC)

Provided herein is a Mouse monoclonal antibody against Human Plakophilin 3. The antibody can be used for immunoassay techniques, such as WB, IHC, ICC, IF, IHC-Fr.
See all PKP3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Dog
Clone
12B11F8
Antibody Isotype
IgG1
Application
WB, IHC, ICC, IF, IHC-Fr

Basic Information

Specificity
Human, Mouse, Dog
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
plakophilin 3
Introduction
PKP3 is a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.
Entrez Gene ID
Human11187
Mouse56460
Dog483399
UniProt ID
HumanQ9Y446
MouseQ9QY23
DogF1PY11
Alternative Names
Plakophilin 3b
Function
May play a role in junctional plaques.
Biological Process
Cell-cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell junction assemblyManual Assertion Based On ExperimentIBA:GO_Central
Desmosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of mRNA catabolic processManual Assertion Based On ExperimentIMP:CAFA
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:CAFA
Protein localization to plasma membraneManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Cell junction, desmosome
Nuclear and associated with desmosomes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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