PKP3

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. [provided by RefSeq]

plakophilin 3

May play a role in junctional plaques.

Cell-cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell junction assemblyManual Assertion Based On ExperimentIBA:GO_Central
Desmosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of mRNA catabolic processManual Assertion Based On ExperimentIMP:CAFA
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:CAFA
Protein localization to plasma membraneManual Assertion Based On ExperimentIMP:UniProtKB

Nucleus
Cell junction, desmosome
Nuclear and associated with desmosomes.