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Mouse Anti-PKP3 Recombinant Antibody (6E5) (CBMAB-A6759-LY)

The product is antibody recognizes PKP3. The antibody 6E5 immunoassay techniques such as: WB, ELISA.
See all PKP3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6E5
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
PKP3 (NP_009114, 225 a.a. ~ 324 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
plakophilin 3
Introduction
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. [provided by RefSeq]
Entrez Gene ID
11187
UniProt ID
Q9Y446
Function
May play a role in junctional plaques.
Biological Process
Cell-cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell junction assemblyManual Assertion Based On ExperimentIBA:GO_Central
Desmosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of mRNA catabolic processManual Assertion Based On ExperimentIMP:CAFA
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:CAFA
Protein localization to plasma membraneManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Cell junction, desmosome
Nuclear and associated with desmosomes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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