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Mouse Anti-PLCB2 Recombinant Antibody (1B3) (CBMAB-P2047-YC)

Provided herein is a Mouse monoclonal antibody against Human Phospholipase C beta 2. The antibody can be used for immunoassay techniques, such as ELISA.
See all PLCB2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B3
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phospholipase C, beta 2
Introduction
PLCB2 is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
Entrez Gene ID
UniProt ID
Alternative Names
PLC-beta-2
Function
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Biological Process
Activation of phospholipase C activityManual Assertion Based On ExperimentTAS:ProtInc
Detection of chemical stimulus involved in sensory perception of bitter tasteIEA:Ensembl
G protein-coupled receptor signaling pathwayTAS:Reactome
Lipid catabolic processIEA:UniProtKB-KW
Phosphatidylinositol metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Phosphatidylinositol-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Phospholipase C-activating G protein-coupled receptor signaling pathwayIEA:Ensembl
Phospholipid metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
cytosol
G-protein beta/gamma-subunit complex
Golgi apparatus
plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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