Mouse Anti-PLD1 Recombinant Antibody (10H2) (CBMAB-P2073-YC)

Name: Mouse Anti-PLD1 Recombinant Antibody (10H2)
SKU: CBMAB-P2073-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

10H2

Application

ELISA, WB

Immunogen

PLD1 (NP_002653, 965-1075 aa) partial recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

phospholipase D1, phosphatidylcholine-specific

Introduction

PLD1 is a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking.

Entrez Gene ID

5337

UniProt ID

Q13393

Alternative Names

HPLD1; Phospholipase D1, Phosphatidylcholine-Specific

Function

Function as phospholipase selective for phosphatidylcholine (PubMed:8530346, PubMed:9582313).
Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).

Biological Process

ChemotaxisManual Assertion Based On ExperimentTAS:ProtInc
Inositol lipid-mediated signalingIEA:InterPro
Phosphatidic acid biosynthetic processTAS:Reactome
Phospholipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of translationManual Assertion Based On ExperimentIMP:CACAO
Ras protein signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Regulation of microvillus assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of synaptic vesicle cycleManual Assertion Based On ExperimentIDA:SynGO
Regulation of vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cytoplasm, perinuclear region
Endoplasmic reticulum membrane
Golgi apparatus membrane
Late endosome membrane

Involvement in disease

Cardiac valvular defect, developmental (CVDD):
An autosomal recessive form of congenital heart defects, characterized by valvular malformations involving the pulmonic, tricuspid and mitral valves.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-PLD1 Recombinant Antibody (2F3) (CAT#: CBMAB-A6786-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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