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Mouse Anti-PLXNC1 Recombinant Antibody (CBT2922) (V2LY-0625-LY1195)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT2922
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
Purified recombinant fragment of human CD232 (AA: extra 35-234) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
plexin C1
Entrez Gene ID
10154
UniProt ID
O60486
Function
Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).
Biological Process
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Semaphorin-plexin signaling pathway involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Extracellular: 35-944
Helical: 945-965
Cytoplasmic: 966-1568
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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