Mouse Anti-POLE2 Recombinant Antibody (1A3) (CBMAB-P2322-YC)

Name: Mouse Anti-POLE2 Recombinant Antibody (1A3)
SKU: CBMAB-P2322-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1A3

Application

Immunogen

POLE2 (NP_002683, 1-101 aa) partial recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-101

More Infomation

Target

Full Name

polymerase (DNA directed), epsilon 2 (p59 subunit)

Introduction

DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.

Entrez Gene ID

5427

UniProt ID

P56282

Alternative Names

DPE2

Function

Accessory component of the DNA polymerase epsilon complex (PubMed:10801849).
Participates in DNA repair and in chromosomal DNA replication (By similarity).

Biological Process

DNA repairManual Assertion Based On ExperimentTAS:ProtInc
DNA replicationManual Assertion Based On ExperimentTAS:ProtInc
DNA-templated DNA replicationManual Assertion Based On ExperimentIDA:ComplexPortal
Error-prone translesion synthesisManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-POLE2 Recombinant Antibody (CBYCD-494) (CAT#: CBMAB-D2182-YC)

Mouse Anti-POLE2 Recombinant Antibody (CBYC-P497) (CAT#: CBMAB-P2323-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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