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Mouse Anti-POLE2 Recombinant Antibody (CBYCD-494) (CBMAB-D2182-YC)

Provided herein is a Mouse monoclonal antibody, which binds to DNA Polymerase Epsilon 2, Accessory Subunit (POLE2). The antibody can be used for immunoassay techniques, such as WB, FC.
See all POLE2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYCD-494
Antibody Isotype
IgG1
Application
WB, FC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
polymerase (DNA directed), epsilon 2 (p59 subunit)
Introduction
DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.
Entrez Gene ID
UniProt ID
Alternative Names
DPE2
Function
Accessory component of the DNA polymerase epsilon complex (PubMed:10801849).
Participates in DNA repair and in chromosomal DNA replication (By similarity).
Biological Process
DNA repairManual Assertion Based On ExperimentTAS:ProtInc
DNA replicationManual Assertion Based On ExperimentTAS:ProtInc
DNA-templated DNA replicationManual Assertion Based On ExperimentIDA:ComplexPortal
Error-prone translesion synthesisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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