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Mouse Anti-PPP1R14A Recombinant Antibody (3A7) (CBMAB-A6964-LY)

The product is antibody recognizes PPP1R14A. The antibody 3A7 immunoassay techniques such as: WB, ELISA.
See all PPP1R14A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3A7
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
PPP1R14A (AAH21089, 1 a.a. ~ 147 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
protein phosphatase 1, regulatory (inhibitor) subunit 14A
Introduction
PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase (see MIM 603768). Inhibition leads to increased myosin phosphorylation and enhances smooth muscle contraction in the absence of increased intracellular Ca(2+) concentration.[supplied by OMIM
Entrez Gene ID
94274
UniProt ID
Q96A00
Alternative Names
CPI-17; CPI17; PPP1INL
Function
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Biological Process
Regulation of phosphorylationIEA:InterPro
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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