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Mouse Anti-PPP1R14A Recombinant Antibody (CBXC-2564) (CBMAB-C0239-CQ)

This product is a mouse antibody that recognizes PPP1R14A. The antibody CBXC-2564 can be used for immunoassay techniques such as: WB, ELISA.
See all PPP1R14A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-2564
Antibody Isotype
IgG2a
Application
WB, ELISA

Basic Information

Immunogen
Recombinant human PPP1R14A (1-147aa) purified from E. coli
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
protein phosphatase 1, regulatory (inhibitor) subunit 14A
Introduction
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Entrez Gene ID
94274
UniProt ID
Q96A00
Alternative Names
CPI-17; CPI17; PPP1INL
Function
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Biological Process
Regulation of phosphorylationIEA:InterPro
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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