Rabbit Anti-PRKAR1A Recombinant Antibody (
1C3) (V2LY-0725-LY852)
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Positive WB detected in: U87 whole cell lysate
All lanes: PRKAR1A antibody at 1.1μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 43, 39 KDa
Observed band size: 43 KDa
Basic Information
| Application | Note |
| WB | 1:500-1:5,000 |
| IF | 1:20-1:200 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Intracellular signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Mesoderm formationIEA:Ensembl
Negative regulation of activated T cell proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of cAMP-dependent protein kinase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentTAS:ProtInc
Sarcomere organizationIEA:Ensembl
CNC is a multiple neoplasia syndrome characterized by spotty skin pigmentation, cardiac and other myxomas, endocrine tumors, and psammomatous melanotic schwannomas.
Intracardiac myxoma (INTMYX):
Inheritance is autosomal recessive.
Primary pigmented nodular adrenocortical disease 1 (PPNAD1):
A rare bilateral adrenal defect causing ACTH-independent Cushing syndrome. Macroscopic appearance of the adrenals is characteristic with small pigmented micronodules observed in the cortex. Clinical manifestations of Cushing syndrome include facial and truncal obesity, abdominal striae, muscular weakness, osteoporosis, arterial hypertension, diabetes. PPNAD1 is most often diagnosed in patients with Carney complex, a multiple neoplasia syndrome. However it can also be observed in patients without other manifestations.
Acrodysostosis 1, with or without hormone resistance (ACRDYS1):
A form of skeletal dysplasia characterized by short stature, severe brachydactyly, facial dysostosis, and nasal hypoplasia. Affected individuals often have advanced bone age and obesity. Laboratory studies show resistance to multiple hormones, including parathyroid, thyrotropin, calcitonin, growth hormone-releasing hormone, and gonadotropin. However, not all patients show endocrine abnormalities.
1C3)?
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Human Recombinant PRKAR1A protein, His Tag (CAT#: V2LY-0526-LY6301)
Rabbit Anti-PRKAR1A Recombinant Antibody (D54D9) (CAT#: CBMAB-P2808-YC)
Mouse Recombinant PRKAR1A protein, His Tag (CAT#: V2LY-0526-LY8797)
Rabbit Anti-PRKAR1A Recombinant Antibody (CBNH-089) (CAT#: CBMAB-R4414-CN)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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