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Mouse Anti-PTGER2 Recombinant Antibody (3F12) (CBMAB-P3321-YC)

Provided herein is a Mouse monoclonal antibody against Human Prostaglandin E Receptor 2. The antibody can be used for immunoassay techniques, such as WB.
See all PTGER2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
3F12
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Recombinanthuman EP2 and EP3 receptor protein and mouse myeloma cells
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Prostaglandin E Receptor 2
Introduction
PTGER2 is a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma
Entrez Gene ID
Human5732
Mouse19217
Rat81752
UniProt ID
HumanP43116
MouseQ62053
RatQ62928
Alternative Names
EP2; Ptgerep2
Function
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathwayISS:BHF-UCL
Cellular response to prostaglandin E stimulusISS:BHF-UCL
G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cytosolic calcium ion concentrationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell population proliferationIEA:Ensembl
Response to lipopolysaccharideIEA:Ensembl
Response to nematodeIEA:Ensembl
Response to progesteroneIEA:Ensembl
Cellular Location
Cell membrane
Topology
Extracellular: 1-23
Helical: 24-47
Cytoplasmic: 48-65
Helical: 66-91
Extracellular: 92-111
Helical: 112-132
Cytoplasmic: 133-151
Helical: 152-176
Extracellular: 177-198
Helical: 199-223
Cytoplasmic: 224-262
Helical: 263-286
Extracellular: 287-299
Helical: 300-323
Cytoplasmic: 324-358
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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