Mouse Anti-PTGER2 Recombinant Antibody (3F12) (CBMAB-P3321-YC)

Name: Mouse Anti-PTGER2 Recombinant Antibody (3F12)
SKU: CBMAB-P3321-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3F12

Application

Immunogen

Recombinanthuman EP2 and EP3 receptor protein and mouse myeloma cells

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Prostaglandin E Receptor 2

Introduction

PTGER2 is a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma

Entrez Gene ID

Human	5732
Mouse	19217
Rat	81752

UniProt ID

Human	P43116
Mouse	Q62053
Rat	Q62928

Alternative Names

EP2; Ptgerep2

Function

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

Biological Process

Adenylate cyclase-activating G protein-coupled receptor signaling pathwayISS:BHF-UCL
Cellular response to prostaglandin E stimulusISS:BHF-UCL
G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cytosolic calcium ion concentrationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell population proliferationIEA:Ensembl
Response to lipopolysaccharideIEA:Ensembl
Response to nematodeIEA:Ensembl
Response to progesteroneIEA:Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 1-23
Helical: 24-47
Cytoplasmic: 48-65
Helical: 66-91
Extracellular: 92-111
Helical: 112-132
Cytoplasmic: 133-151
Helical: 152-176
Extracellular: 177-198
Helical: 199-223
Cytoplasmic: 224-262
Helical: 263-286
Extracellular: 287-299
Helical: 300-323
Cytoplasmic: 324-358

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-PTGER2 Recombinant Antibody (CBYC-P748) (CAT#: CBMAB-P3322-YC)

Rabbit Anti-PTGER2 Recombinant Antibody (
8D8) (CAT#: V2LY-0725-LY1281)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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