Mouse Anti-PTGES Recombinant Antibody (CBFYM-3082) (CBMAB-M3278-FY)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Plays a key role in inflammation response, fever and pain (By similarity).
Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2 (PubMed:12244105, PubMed:12672824).
In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively (PubMed:12672824).
Negative regulation of cell population proliferationIEA:Ensembl
Positive regulation of prostaglandin secretionIEA:Ensembl
Prostaglandin biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Prostaglandin metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Regulation of fever generationISS:UniProtKB
Regulation of inflammatory responseISS:UniProtKB
Sensory perception of painISS:UniProtKB
Signal transduction1 PublicationNAS:ProtInc
Cytoplasm, perinuclear region
Colocalizes with PTGS1/COX-1 and PTGS2/COX-2 in the perinuclear compartment.
Helical: 13-41
Cytoplasmic: 42-60
Helical: 61-90
Lumenal: 91-95
Helical: 96-119
Cytoplasmic: 120-123
Helical: 124-152
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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