Mouse Anti-PTGES2 Recombinant Antibody (5B7) (CBMAB-P3328-YC)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
The biological function and the GSH-dependent property of PTGES2 is still under debate (PubMed:18198127, PubMed:17585783).
In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA) (PubMed:17585783) (By similarity).
Glutathione metabolic processIEA:InterPro
Lipid metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription, DNA-templatedIEA:Ensembl
SecretionIEA:Ensembl
Prostaglandin E synthase
Cytoplasm, perinuclear region
Synthesized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. The truncated form is cytoplasmic and is enriched in the perinuclear region.
Helical: 58-74
Cytoplasmic: 75-377
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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