Mouse Anti-PTGIR Recombinant Antibody (CBYY-I1562) (CBMAB-I2732-YY)

Name: Mouse Anti-PTGIR Recombinant Antibody (CBYY-I1562)
SKU: CBMAB-I2732-YY
Rating: 5 (1 reviews)

See all PTGIR antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-I1562

Application

WB, IP, IF, ELISA

Specificity

Human, Mouse, Rat

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

prostaglandin I2 (prostacyclin) receptor (IP)

Introduction

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

Entrez Gene ID

Human	5739
Mouse	19222
Rat	292661

UniProt ID

Human	P43119
Mouse	P43252
Rat	P43253

Alternative Names

IP; PRIPR

Function

Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.

Biological Process

Adenylate cyclase-activating G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of platelet-derived growth factor receptor signaling pathwayBy SimilarityISS:BHF-UCL
Negative regulation of smooth muscle cell proliferationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of cytosolic calcium ion concentrationManual Assertion Based On ExperimentIBA:GO_Central
Response to lipopolysaccharideIEA:Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 1-16
Helical: 17-38
Cytoplasmic: 39-51
Helical: 52-76
Extracellular: 77-94
Helical: 95-115
Cytoplasmic: 116-134
Helical: 135-158
Extracellular: 159-181
Helical: 182-208
Cytoplasmic: 209-235
Helical: 236-260
Extracellular: 261-274
Helical: 275-295
Cytoplasmic: 296-386

PTM

Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-PTGIR Recombinant Antibody (CBYY-I1562)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PTGIR Recombinant Antibody (2A7) (CAT#: CBMAB-A7175-LY)

Mouse Anti-PTGIR Recombinant Antibody (4B10) (CAT#: CBMAB-P3333-YC)

Mouse Anti-PTGIR Recombinant Antibody (CBYC-P753) (CAT#: CBMAB-P3335-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry