Sign in or Register   Sign in or Register
  |  

Mouse Anti-PTPN5 Recombinant Antibody (2H5) (CBMAB-A7226-LY)

The product is antibody recognizes PTPN5. The antibody 2H5 immunoassay techniques such as: IP, ELISA.
See all PTPN5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2H5
Antibody Isotype
IgG1, κ
Application
IP, ELISA

Basic Information

Immunogen
PTPN5 (NP_116170, 388 a.a. ~ 486 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
PTPN5
Entrez Gene ID
84867
UniProt ID
P54829
Alternative Names
FLJ14427; PTPSTEP; STEP
Function
May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
Biological Process
Peptidyl-tyrosine dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Protein dephosphorylationManual Assertion Based On ExperimentTAS:UniProtKB
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endoplasmic reticulum membrane
PTM
Phosphorylation at Ser-245 by PKA deactivates PTPN5. Phosphorylation at Thr-255 and Ser-268 by MAPKs stabilizes the phosphatase, dephosphorylation of these sites results in ubiquitin-mediated degradation of the active phosphatase.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-PTPN5 Recombinant Antibody (2H5)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare