Mouse Anti-PTPN7 Recombinant Antibody (AFPK32) (CBMAB-H4199-FY)

Name: Mouse Anti-PTPN7 Recombinant Antibody (AFPK32)
SKU: CBMAB-H4199-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

AFPK32

Application

Immunogen

Recombinant human protein purified from E.coli

Specificity

Human

Antibody Isotype

IgG1, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

HEPES, 0.15M NaCl, 0.01% BSA, 50% glycerol

Preservative

0.03% Sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Protein tyrosine phosphatase, non-receptor type 7

Introduction

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.

Entrez Gene ID

5778

UniProt ID

B4DZD9

Alternative Names

LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP

Function

Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.

Biological Process

MAPK cascadeTAS:Reactome
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Cytoplasm, cytoskeleton

PTM

Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases.
Oxidized at active site cysteine. Treatment with pervanadate (vanadate and H2O2) or with antigen enhanced oxidation of active site cysteine (By similarity).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-PTPN7 Recombinant Antibody (3B10) (CAT#: CBMAB-P3448-YC)

Mouse Anti-PTPN7 Recombinant Antibody (CBFYH-3640) (CAT#: CBMAB-H4200-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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