Mouse Anti-PTPRZ1 Recombinant Antibody (3F8) (CBMAB-0184-CN)

Name: Mouse Anti-PTPRZ1 Recombinant Antibody (3F8)
SKU: CBMAB-0184-CN
Rating: 5 (1 reviews)

See all PTPRZ1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3F8

Application

ELISA

Specificity

Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

>95%, as determined by SDS-PAGE analysis

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Protein tyrosine phosphatase, receptor type Z1

Introduction

This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. The protein is required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis.

Entrez Gene ID

25613

UniProt ID

Q62656

Alternative Names

Ptpz; RPTPbeta; PTPzeta-A; PTPzeta-B; PTPzeta-S

Function

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity).

Biological Process

AxonogenesisIEA:Ensembl
Central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Hematopoietic progenitor cell differentiationIEA:Ensembl
Learning or memoryISS:UniProtKB
Negative regulation of neuron apoptotic processISS:UniProtKB
Oligodendrocyte differentiationISS:UniProtKB
Peptidyl-tyrosine dephosphorylationISS:UniProtKB
Positive regulation of oligodendrocyte differentiationISS:UniProtKB
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of myelinationISS:UniProtKB
Regulation of oligodendrocyte progenitor proliferationISS:UniProtKB

Cellular Location

Isoform 1
Cell membrane
Secreted
A secreted form is apparently generated by shedding of the extracellular domain.
Isoform 2
Secreted

Topology

Extracellular: 25-1636
Helical: 1637-1662
Cytoplasmic: 1663-2315

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-PTPRZ1 Recombinant Antibody (3F8)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rat Anti-PTPRZ1 Recombinant Antibody (279245) (CAT#: CBMAB-1739-CN)

Mouse Anti-PTPRZ1 Recombinant Antibody (2B49) (CAT#: CBMAB-0125-CN)

Mouse Anti-PTPRZ1 Recombinant Antibody (CBYC-P791) (CAT#: CBMAB-P3499-YC)

Mouse Anti-PTPRZ1 Recombinant Antibody (CBYC-P790) (CAT#: CBMAB-P3498-YC)

Mouse Anti-PTPRZ1 Recombinant Antibody (122.2) (CAT#: CBMAB-1737-CN)

Rat Anti-PTPRZ1 Recombinant Antibody (279244) (CAT#: CBMAB-1738-CN)

Mouse Anti-PTPRZ1 Recombinant Antibody (3H1) (CAT#: CBMAB-0185-CN)

Mouse Anti-PTPRZ1 Recombinant Antibody (MM0887-36D27) (CAT#: CBMAB-1740-CN)

Mouse Anti-PTPRZ1 Recombinant Antibody (12/RPTPb) (CAT#: CBMAB-R0670-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry