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Recombinant Mouse Anti-RAB27B Antibody (CBAb203) (CBMAB-Ab203-LY)

The product is antibody recognizes RAB27B. The antibody CBAb203 immunoassay techniques such as: WB 1:500-1:2000; FC 1:20-1:50.
See all RAB27B antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBAb203
Antibody Isotype
IgG
Application
WB 1:500-1:2000; FC 1:20-1:50

Basic Information

Immunogen
A synthetic peptide of human RAB27B
Specificity
Human, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
RAB27B, member RAS oncogene family
Introduction
Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking.
Entrez Gene ID
Human5874
Mouse80718
UniProt ID
HumanO00194
MouseQ99P58
Alternative Names
RAB27B; C25KG; ras-related protein Rab-27B
Function
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381).
Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604).
May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
Biological Process
Biological Process anterograde axonal protein transportISS:UniProtKB
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process multivesicular body sorting pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synaptic vesicle endocytosisIEA:Ensembl
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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