RAB27B
Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking.
Full Name
RAB27B, member RAS oncogene family
Function
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381).
Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604).
May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604).
May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
Biological Process
Biological Process anterograde axonal protein transportISS:UniProtKB
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process multivesicular body sorting pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synaptic vesicle endocytosisIEA:Ensembl
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process multivesicular body sorting pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synaptic vesicle endocytosisIEA:Ensembl
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
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Anti-RAB27B antibodies
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Target: RAB27B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBAb203
Application*: WB, FC
Target: RAB27B
Host: Mouse
Specificity: Human, Mouse
Clone: CBCNR-029
Application*: WB, F
Target: RAB27B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 1596CT245.254.49
Application*: WB
Target: RAB27B
Sensitivity: 0.009 ng/mL
Detection Range: 0.02-3.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: RAB27B
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 2-215
Tag: Fc Tag
Target: RAB27B
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 2-215
Tag: His Tag
Target: RAB27B
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 2-215
Target: RAB27B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3457
Application*: IH, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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