RAB27B

Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking.

RAB27B, member RAS oncogene family

Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381).
Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604).
May be involved in targeting uroplakins to urothelial apical membranes (By similarity).

Biological Process anterograde axonal protein transportISS:UniProtKB
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process multivesicular body sorting pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synaptic vesicle endocytosisIEA:Ensembl
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central