Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-RAB2A Recombinant Antibody (2B12-1D8-A5-A9) (CBMAB-R0801-CN)


See all RAB2A antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Cattle, Cat, Dog, Human, Pig, Zebrafish
Clone
2B12-1D8-A5-A9
Antibody Isotype
IgG1
Application
WB, IF

Basic Information

Specificity
Mouse, Rat, Cattle, Cat, Dog, Human, Pig, Zebrafish
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL

Target

Full Name
RAB2A, Member RAS Oncogene Family
Introduction
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Entrez Gene ID
Human5862
Mouse59021
Rat65158
Cattle508373
Dog404009
Cat101083739
Pig100151822
Zebrafish140617
UniProt ID
HumanP61019
MouseP53994
RatP05712
CattleQ148J4
DogP61105
CatM3X7S2
PigF1RT87
ZebrafishQ803J3
Alternative Names
RAB2A, Member RAS Oncogene Family; RAB2, Member RAS Oncogene Family; RAB2; Small GTP Binding Protein RAB2A; Ras-Related Protein Rab-2A; LHX;
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi.
Biological Process
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentTAS:ProtInc
Biological Process Golgi organizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane
Melanosome
Endoplasmic reticulum membrane
Golgi apparatus membrane
Cytoplasmic vesicle, secretory vesicle, acrosome
Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid (By similarity).
Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-RAB2A Recombinant Antibody (2B12-1D8-A5-A9)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry