Mouse Anti-RANBP9 Recombinant Antibody (3C3-E11-C12) (CBMAB-R1281-CN)

Name: Mouse Anti-RANBP9 Recombinant Antibody (3C3-E11-C12)
SKU: CBMAB-R1281-CN
Rating: 5 (1 reviews)

See all RANBP9 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3C3-E11-C12

Application

WB, IP, IF

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1 mg/mL

More Infomation

Target

Full Name

RAN Binding Protein 9

Introduction

This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]

Entrez Gene ID

10048

UniProt ID

Q96S59

Alternative Names

RAN Binding Protein 9; Ran Binding Protein In The Microtubule Organizing Center; Ran-Binding Protein M; RANBP7; RANBPM; BPM-L;

Function

May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement (PubMed:18710924).
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (PubMed:29911972).
May be involved in signaling of ITGB2/LFA-1 and other integrins (PubMed:14722085).
Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway (PubMed:12147692).
Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation (PubMed:12361945, PubMed:18222118).
Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity (PubMed:15558019).
Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.

Biological Process

Biological Process cell surface receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process microtubule nucleationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of ERK1 and ERK2 cascadeManual Assertion Based On ExperimentIMP:CACAO
Biological Process positive regulation of amyloid precursor protein catabolic processISS:ARUK-UCL
Biological Process protein-containing complex assemblyManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cytoplasm
Nucleus
Cell membrane
The unphosphorylated form is predominantly cytoplasmic. A phosphorylated form is associated with the plasma membrane.

PTM

Phosphorylated in response to stress. Can be phosphorylated by the cleaved p110 form of CDC2L1 (p110C).
Ubiquitinated. Polyubiquitination targets the protein for rapid degradation via the ubiquitin system. Can be deubiquitinated by USP11.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-RANBP9 Recombinant Antibody (3C3-E11-C12)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

rabbit Anti-RANBP9 Recombinant Antibody (D8M8D) (CAT#: CBMAB-R1286-CN)

Mouse Anti-RANBP9 Recombinant Antibody (13k114) (CAT#: CBMAB-R1279-CN)

Mouse Anti-RANBP9 Recombinant Antibody (CBCNR-182) (CAT#: CBMAB-R1285-CN)

Recombinant Mouse Anti-RANBP9 Antibody (CBAb210) (CAT#: CBMAB-Ab210-LY)

Mouse Anti-RanBP9 Recombinant Antibody (2H2-E8-B7) (CAT#: CBMAB-Z0357-LY)

Rabbit Anti-RANBP9 Recombinant Antibody (CBCNR-179) (CAT#: CBMAB-R1282-CN)

Mouse Anti-RANBP9 Recombinant Antibody (CBCNR-181) (CAT#: CBMAB-R1284-CN)

Mouse Anti-RANBP9 Recombinant Antibody (CBT2561) (CAT#: V2LY-0625-LY136)

Mouse Anti-RANBP9 Recombinant Antibody (M80544) (CAT#: CBMAB-R1287-CN)

Mouse Anti-RANBP9 Recombinant Antibody (15B240) (CAT#: CBMAB-R1280-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry