Mouse Anti-RASA3 Recombinant Antibody (CBFYH-2726) (CBMAB-H0759-FY)

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBFYH-2726
Application
ELISA, WB
Specificity
Pig
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
RAS p21 protein activator 3
Introduction
This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
UniProt ID
Alternative Names
RAS P21 Protein Activator 3; Ins P4-Binding Protein; GTPase-Activating Protein 1 Family, Inositol 1,3,4,5-Tetrakisphosphate-Binding Protein; Ras GTPase-Activating Protein 3; Ins(1,3,4,5)P4-Binding Protein; GTPase Activating Protein III; GAP1(IP4BP); GAP1IP4BP; GAPIII
Function
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.
Biological Process
Biological Process negative regulation of Ras protein signal transductionIEA:InterPro
Biological Process regulation of GTPase activityIEA:InterPro
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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