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Mouse Anti-RASA3 Recombinant Antibody (GP-3) (CBMAB-R1467-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
GP-3
Antibody Isotype
IgG2b
Application
WB, ELISA, ICC

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
2 mg/mL

Target

Full Name
RAS p21 protein activator 3
Introduction
This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Entrez Gene ID
22821
UniProt ID
Q14644
Alternative Names
RAS P21 Protein Activator 3; Ins P4-Binding Protein; GTPase-Activating Protein 1 Family, Inositol 1,3,4,5-Tetrakisphosphate-Binding Protein; Ras GTPase-Activating Protein 3; Ins(1,3,4,5)P4-Binding Protein; GTPase Activating Protein III; GAP1(IP4BP); GAP1IP4BP; GAPIII;
Function
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.
Biological Process
Biological Process negative regulation of Ras protein signal transductionIEA:InterPro
Biological Process regulation of GTPase activityIEA:InterPro
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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