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Mouse Anti-RBBP9 Recombinant Antibody (1C10) (CBMAB-R1658-CN)

This product is a Mouse antibody that recognizes RBBP9. The antibody 1C10 can be used for immunoassay techniques such as: WB, IF, FC.
See all RBBP9 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C10
Antibody Isotype
IgG1
Application
WB, IF, FC

Basic Information

Immunogen
Full length human recombinant protein of human RBBP9 (NP_006597) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Concentration
0.29 mg/mL

Target

Full Name
RB Binding Protein 9, Serine Hydrolase
Introduction
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008]
Entrez Gene ID
UniProt ID
Alternative Names
RB Binding Protein 9, Serine Hydrolase; Retinoblastoma-Binding Protein 9; Retinoblastoma-Binding Protein 10; RBBP-10; RBBP-9; RBBP10; BOG; Retinoblastoma Binding Protein 9;
Function
Serine hydrolase whose substrates have not been identified yet (PubMed:19329999, PubMed:20080647).
May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation (PubMed:20080647).
May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1 (PubMed:9697699).
Biological Process
Biological Process positive regulation of gene expressionIEA:Ensembl
Biological Process regulation of cell population proliferationIEA:Ensembl
Biological Process response to nematodeIEA:Ensembl
Biological Process type II pneumocyte differentiationIEA:Ensembl
Cellular Location
Nucleoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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