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Rabbit Anti-RBBP9 Recombinant Antibody (CBCNR-287) (CBMAB-R1667-CN)


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Summary

Host Animal
Rabbit
Specificity
Rat, Human
Clone
CBCNR-287
Antibody Isotype
IgG
Application
WB, IHC-P, FC, IF

Basic Information

Specificity
Rat, Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RB Binding Protein 9, Serine Hydrolase
Introduction
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human10741
Rat29459
UniProt ID
HumanO75884
RatO88350
Alternative Names
RB Binding Protein 9, Serine Hydrolase; Retinoblastoma-Binding Protein 9; Retinoblastoma-Binding Protein 10; RBBP-10; RBBP-9; RBBP10; BOG; Retinoblastoma Binding Protein 9;
Function
Serine hydrolase whose substrates have not been identified yet (PubMed:19329999, PubMed:20080647).
May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation (PubMed:20080647).
May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1 (PubMed:9697699).
Biological Process
Biological Process positive regulation of gene expressionIEA:Ensembl
Biological Process regulation of cell population proliferationIEA:Ensembl
Biological Process response to nematodeIEA:Ensembl
Biological Process type II pneumocyte differentiationIEA:Ensembl
Cellular Location
Nucleoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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