RBBP9

The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008]
Full Name
RB Binding Protein 9, Serine Hydrolase
Function
Serine hydrolase whose substrates have not been identified yet (PubMed:19329999, PubMed:20080647).
May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation (PubMed:20080647).
May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1 (PubMed:9697699).
Biological Process
Biological Process positive regulation of gene expressionIEA:Ensembl
Biological Process regulation of cell population proliferationIEA:Ensembl
Biological Process response to nematodeIEA:Ensembl
Biological Process type II pneumocyte differentiationIEA:Ensembl
Cellular Location
Nucleoplasm
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Anti-RBBP9 antibodies

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Target: RBBP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF363
Application*: ELISA, WB, IHC
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF362
Application*: ELISA, WB, IF, IHC
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNR-290
Application*: WB
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-289
Application*: E, WB, IH
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-288
Application*: E, WB, IF, IH
Target: RBBP9
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat, Human
Clone: CBCNR-287
Application*: WB, P, F, IF
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4G9
Application*: WB, IH, IF, F
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4G3
Application*: WB, IH, IF, F
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E1
Application*: IF, WB
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3D5E11
Application*: E, WB, IH
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2G2
Application*: WB, IF, F
Target: RBBP9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C10
Application*: WB, IF, F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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