RBBP9

The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008]

Full Name

RB Binding Protein 9, Serine Hydrolase

Function

Serine hydrolase whose substrates have not been identified yet (PubMed:19329999, PubMed:20080647).
May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation (PubMed:20080647).
May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1 (PubMed:9697699).

Biological Process

Biological Process positive regulation of gene expressionIEA:Ensembl
Biological Process regulation of cell population proliferationIEA:Ensembl
Biological Process response to nematodeIEA:Ensembl
Biological Process type II pneumocyte differentiationIEA:Ensembl

Cellular Location

Nucleoplasm

Anti-RBBP9 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-RBBP9 Recombinant Antibody (CF363) (CBMAB-FT142LY)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CF363

Application*: ELISA, WB, IHC

Mouse Anti-RBBP9 Recombinant Antibody (CF362) (CBMAB-FT138LY)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CF362

Application*: ELISA, WB, IF, IHC

Mouse Anti-RBBP9 Recombinant Antibody (CBCNR-290) (CBMAB-R1670-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBCNR-290

Application*: WB

Mouse Anti-RBBP9 Recombinant Antibody (CBCNR-289) (CBMAB-R1669-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBCNR-289

Application*: E, WB, IH

Mouse Anti-RBBP9 Recombinant Antibody (CBCNR-288) (CBMAB-R1668-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBCNR-288

Application*: E, WB, IF, IH

Rabbit Anti-RBBP9 Recombinant Antibody (CBCNR-287) (CBMAB-R1667-CN)

Datasheet

SDS

Target: RBBP9

Host: Rabbit

Antibody Isotype: IgG

Specificity: Rat, Human

Clone: CBCNR-287

Application*: WB, P, F, IF

Mouse Anti-RBBP9 Recombinant Antibody (4G9) (CBMAB-R1666-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 4G9

Application*: WB, IH, IF, F

Mouse Anti-RBBP9 Recombinant Antibody (4G3) (CBMAB-R1665-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 4G3

Application*: WB, IH, IF, F

Mouse Anti-RBBP9 Recombinant Antibody (4E1) (CBMAB-R1664-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4E1

Application*: IF, WB

Mouse Anti-RBBP9 Recombinant Antibody (3D5E11) (CBMAB-R1662-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 3D5E11

Application*: E, WB, IH

Mouse Anti-RBBP9 Recombinant Antibody (2G2) (CBMAB-R1661-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2G2

Application*: WB, IF, F

Mouse Anti-RBBP9 Recombinant Antibody (1C10) (CBMAB-R1658-CN)

Datasheet

SDS

Target: RBBP9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1C10

Application*: WB, IF, F

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)