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Mouse Anti-RBFOX2 Recombinant Antibody (CBT4157) (V2LY-0625-LY1196)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4157
Antibody Isotype
IgG1
Application
IHC, FC

Basic Information

Immunogen
Purified recombinant fragment of human RBFOX2 (AA: 1-145) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
RNA Binding Fox-1 Homolog 2
Entrez Gene ID
23543
Function
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity).
RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.
Biological Process
Biological Process intracellular estrogen receptor signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process nervous system developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of alternative mRNA splicing, via spliceosomeISS:BHF-UCL
Biological Process regulation of cell population proliferationManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process RNA metabolic processManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process RNA splicingIEA:UniProtKB-KW
Cellular Location
Nucleus
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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