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Mouse Anti-RCN1 Recombinant Antibody (1F8-E4) (CBMAB-R1935-CN)

This product is a Mouse antibody that recognizes RCN1. The antibody 1F8-E4 can be used for immunoassay techniques such as: ELISA, WB.
See all RCN1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F8-E4
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to human RCN1, aa. 31-331 (H10120) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
reticulocalbin 1, EF-hand calcium binding domain
Introduction
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane. [provided by RefSeq, Jan 2009]
Entrez Gene ID
5954
UniProt ID
Q15293
Alternative Names
Reticulocalbin 1; Reticulocalbin 1, EF-Hand Calcium Binding Domain; Proliferation-Inducing Gene 20; RCN; Epididymis Secretory Protein Li 84; Reticulocalbin-1; HEL-S-84; PIG20; RCAL;
Function
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
Biological Process
Biological Process camera-type eye developmentIEA:Ensembl
Biological Process in utero embryonic developmentIEA:Ensembl
Cellular Location
Endoplasmic reticulum lumen
PTM
O-glycosylated. O-mannosylated by POMT1 and POMT2 and elongated by POMGNT1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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