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Rabbit Anti-RCN1 Recombinant Antibody (CBCNR-352) (CBMAB-R0179-CN)

This product is a Rabbit antibody that recognizes RCN1. The antibody CBCNR-352 can be used for immunoassay techniques such as: WB, IP, IHC-P, IF.
See all RCN1 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBCNR-352
Antibody Isotype
IgG
Application
WB, IP, IHC-P, IF

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
reticulocalbin 1, EF-hand calcium binding domain
Introduction
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane. [provided by RefSeq, Jan 2009]
Entrez Gene ID
Human5954
Mouse19672
Rat362182
UniProt ID
HumanQ15293
MouseQ05186
RatD3ZUB0
Alternative Names
Reticulocalbin 1; Reticulocalbin 1, EF-Hand Calcium Binding Domain; Proliferation-Inducing Gene 20; RCN; Epididymis Secretory Protein Li 84; Reticulocalbin-1; HEL-S-84; PIG20; RCAL;
Function
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
Biological Process
Biological Process camera-type eye developmentIEA:Ensembl
Biological Process in utero embryonic developmentIEA:Ensembl
Cellular Location
Endoplasmic reticulum lumen
PTM
O-glycosylated. O-mannosylated by POMT1 and POMT2 and elongated by POMGNT1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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