Sign in or Register   Sign in or Register
  |  

Mouse Anti-SDR16C5 Recombinant Antibody (3G8) (CBMAB-A7504-LY)

The product is antibody recognizes RDHE2. The antibody 3G8 immunoassay techniques such as: WB, ELISA.
See all SDR16C5 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
3G8
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
RDHE2 (AAH37219, 26 a.a. ~ 309 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Short Chain Dehydrogenase/Reductase Family 16C Member 5
Introduction
RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).[supplied by OMIM
Entrez Gene ID
Human195814
Mouse242285
Rat297805
UniProt ID
HumanQ8N3Y7
MouseQ7TQA3
RatD3ZS85
Alternative Names
FLJ33105; RDH#2; RDH-E2; RDHE2
Function
Oxidoreductase with strong preference for NAD (PubMed:18926804).
Active in both the oxidative and reductive directions (PubMed:18926804).
Oxidizes all-trans-retinol in all-trans-retinaldehyde (PubMed:18926804).
No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD+/NADH or NADP+/NADPH (PubMed:18926804).
Biological Process
Biological Process keratinocyte proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of histone acetylationManual Assertion Based On ExperimentIDA:CAFA
Biological Process negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:CAFA
Biological Process positive regulation of histone deacetylationManual Assertion Based On ExperimentIDA:CAFA
Biological Process retinal metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process retinol metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Endoplasmic reticulum membrane
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-SDR16C5 Recombinant Antibody (3G8)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare