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Mouse Anti-RIDA Recombinant Antibody (CBFYH-2731) (CBMAB-H0760-FY)

This product is mouse antibody that recognizes RIDA. The antibody CBFYH-2731 can be used for immunoassay techniques such as: ELISA, WB.
See all RIDA antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-2731
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
reactive intermediate imine deaminase A homolog
Introduction
RIDA (Reactive Intermediate Imine Deaminase A Homolog) is a Protein Coding gene.
Entrez Gene ID
10247
UniProt ID
P52758
Alternative Names
Reactive Intermediate Imine Deaminase A Homolog; Heat-Responsive Protein 12; Translation Inhibitor L-PSP Ribonuclease; 14.5 KDa Translational Inhibitor Protein; Translational Inhibitor P14.5; UK114 Antigen Homolog; HRSP12; Hp14.5; P14.5; Reactive Intermediate/Imine Deaminase A Homolog
Function
Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex (PubMed:8973653, PubMed:30930054).
Acts by bridging YTHDF2 and the ribonuclease P/MRP complex (PubMed:30930054).
RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage (PubMed:30930054).
Biological Process
Biological Process brain developmentIEA:Ensembl
Biological Process G1 to G0 transitionIEA:Ensembl
Biological Process kidney developmentIEA:Ensembl
Biological Process L-threonine catabolic process to glycineTAS:Reactome
Biological Process lipid metabolic processIEA:UniProtKB-KW
Biological Process lung developmentIEA:Ensembl
Biological Process mRNA catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA destabilizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of epithelial cell proliferationIEA:Ensembl
Biological Process negative regulation of translationISS:UniProtKB
Biological Process organonitrogen compound catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to lipidIEA:Ensembl
Biological Process response to saltIEA:Ensembl
Cellular Location
Cytoplasm
Nucleus
Peroxisome
Mitochondrion
Mostly cytoplasmic but, in less differentiated cells occasionally nuclear.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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