Mouse Anti-RIDA (AA 1-137) Recombinant Antibody (CBFYH-2733) (CBMAB-H3791-FY)

Name: Mouse Anti-RIDA (AA 1-137) Recombinant Antibody (CBFYH-2733)
SKU: CBMAB-H3791-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYH-2733

Application

ELISA, IF, WB

Immunogen

Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: MSSLIRRVIS TAKAPGAIGP YSQAVLVDRT IYISGQIGMD PSSGQLVSGG VAEEAKQALK NMGEILKAAG CDFTNVVKTT VLLADINDFN TVNEIYKQYF KSNFPARAAY QVAALPKGSR IEIEAVAIQG PLTTASL

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-137

More Infomation

Target

Full Name

reactive intermediate imine deaminase A homolog

Introduction

RIDA (Reactive Intermediate Imine Deaminase A Homolog) is a Protein Coding gene.

Entrez Gene ID

10247

UniProt ID

P52758

Alternative Names

Reactive Intermediate Imine Deaminase A Homolog; Heat-Responsive Protein 12; Translation Inhibitor L-PSP Ribonuclease; 14.5 KDa Translational Inhibitor Protein; Translational Inhibitor P14.5; UK114 Antigen Homolog; HRSP12; Hp14.5; P14.5; Reactive Intermediate/Imine Deaminase A Homolog

Function

Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex (PubMed:8973653, PubMed:30930054).
Acts by bridging YTHDF2 and the ribonuclease P/MRP complex (PubMed:30930054).
RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage (PubMed:30930054).

Biological Process

Biological Process brain developmentIEA:Ensembl
Biological Process G1 to G0 transitionIEA:Ensembl
Biological Process kidney developmentIEA:Ensembl
Biological Process L-threonine catabolic process to glycineTAS:Reactome
Biological Process lipid metabolic processIEA:UniProtKB-KW
Biological Process lung developmentIEA:Ensembl
Biological Process mRNA catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA destabilizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of epithelial cell proliferationIEA:Ensembl
Biological Process negative regulation of translationISS:UniProtKB
Biological Process organonitrogen compound catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to lipidIEA:Ensembl
Biological Process response to saltIEA:Ensembl

Cellular Location

Cytoplasm
Nucleus
Peroxisome
Mitochondrion
Mostly cytoplasmic but, in less differentiated cells occasionally nuclear.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-RIDA (AA 1-137) Recombinant Antibody (CBFYH-2732) (CAT#: CBMAB-H3790-FY)

Mouse Anti-RIDA Recombinant Antibody (2B8) (CAT#: CBMAB-A4095-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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