Rabbit Anti-RNASE1 Recombinant Antibody (058) (CBMAB-R2848-CN)

Name: Rabbit Anti-RNASE1 Recombinant Antibody (058)
SKU: CBMAB-R2848-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

058

Application

ELISA

Immunogen

Recombinant Human RNase A / Ribonuclease A / RNASE1 Protein

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

ribonuclease, RNase A family, 1 (pancreatic)

Introduction

This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Entrez Gene ID

6035

UniProt ID

P07998

Alternative Names

Ribonuclease A Family Member 1, Pancreatic; Ribonuclease, RNase A Family, 1 (Pancreatic); Ribonuclease 1; RNase UpI-1; EC 3.1.27.5; HP-RNase; RNase 1; RNase A;

Function

Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.

Biological Process

Biological Process defense response to Gram-positive bacteriumManual Assertion Based On ExperimentIBA:GO_Central
Biological Process RNA phosphodiester bond hydrolysisManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Secreted

PTM

N-linked glycans are of complex type.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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