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Mouse Anti-RNASE1 Recombinant Antibody (CBCNR-557) (CBMAB-R2851-CN)

This product is a Mouse antibody that recognizes RNASE1. The antibody CBCNR-557 can be used for immunoassay techniques such as: WB, ICC, IHC-P, IHC-Fr, ELISA.
See all RNASE1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-557
Application
WB, ICC, IHC-P, IHC-Fr, ELISA

Basic Information

Immunogen
Ribonuclease A
Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4, 50% Glycerol
Preservative
0.02% Sodium azide
Concentration
0.5 mg/mL

Target

Full Name
ribonuclease, RNase A family, 1 (pancreatic)
Introduction
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Entrez Gene ID
6035
UniProt ID
P07998
Alternative Names
Ribonuclease A Family Member 1, Pancreatic; Ribonuclease, RNase A Family, 1 (Pancreatic); Ribonuclease 1; RNase UpI-1; EC 3.1.27.5; HP-RNase; RNase 1; RNase A;
Function
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.
Biological Process
Biological Process defense response to Gram-positive bacteriumManual Assertion Based On ExperimentIBA:GO_Central
Biological Process RNA phosphodiester bond hydrolysisManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Secreted
PTM
N-linked glycans are of complex type.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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