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Mouse Anti-RRM1 Recombinant Antibody (CBT3252) (V2LY-0625-LY1375)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT3252
Antibody Isotype
IgG2a
Application
WB, IHC, FC

Basic Information

Immunogen
Purified recombinant fragment of human RRM1 (AA: 541-792) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Ribonucleotide Reductase Catalytic Subunit M1
Entrez Gene ID
6240
Function
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Biological Process
Biological Process 2'-deoxyribonucleotide biosynthetic processManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process deoxyribonucleotide biosynthetic processISS:UniProtKB
Biological Process DNA repairManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process DNA synthesis involved in DNA repair1 PublicationIC:ComplexPortal
Biological Process mitochondrial DNA replicationManual Assertion Based On ExperimentIMP:ComplexPortal
Biological Process positive regulation of G0 to G1 transitionManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of G1/S transition of mitotic cell cycleManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of G2/M transition of mitotic cell cycleManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process protein heterotetramerizationIEA:Ensembl
Biological Process ribonucleoside diphosphate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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