Mouse Anti-RTN4RL1 Recombinant Antibody (B-7) (CBMAB-N4237-WJ)

Name: Mouse Anti-RTN4RL1 Recombinant Antibody (B-7)
SKU: CBMAB-N4237-WJ
Rating: 5 (1 reviews)

See all RTN4RL1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

B-7

Application

WB, IP, IF, ELISA

Specificity

Human, Mouse, Rat

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Reticulon 4 Receptor Like 1

Introduction

RTN4RL1 (Reticulon 4 Receptor Like 1) is a Protein Coding gene. Diseases associated with RTN4RL1 include Retrograde Amnesia. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins. Gene Ontology (GO) annotations related to this gene include receptor activity. An important paralog of this gene is RTN4RL2.

Entrez Gene ID

Human	146760
Mouse	237847
Rat	303311

UniProt ID

Human	Q86UN2
Mouse	Q8K0S5
Rat	Q80WD0

Alternative Names

Reticulon 4 Receptor Like 1; Nogo-66 Receptor Homolog 2; Nogo-66 Receptor-Related Protein 3; Nogo Receptor-Like 2; NGRH2; NgR3; Reticulon 4 Receptor-Like 1; Reticulon-4 Receptor-Like 1; NGRL2;

Function

Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity).
Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200).
Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200).

Biological Process

Biological Process axon regenerationManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process corpus callosum developmentIEA:Ensembl
Biological Process negative regulation of axon regenerationISS:UniProtKB
Biological Process negative regulation of neuron projection developmentISS:UniProtKB

Cellular Location

Cell membrane
Membrane raft
Perikaryon
Cell projection
Localized to the surface of neurons, including axons.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-RTN4RL1 Recombinant Antibody (B-7)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-RTN4RL1 Recombinant Antibody (M5) (CAT#: CBMAB-N4239-WJ)

Mouse Anti-RTN4RL1 Recombinant Antibody (H-11) (CAT#: CBMAB-N4238-WJ)

Mouse Anti-RTN4RL1 Recombinant Antibody (CBWJN-1667) (CAT#: CBMAB-N4236-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry