Mouse Anti-SAMD4A Recombinant Antibody (CBXS-2672) (CBMAB-S5424-CQ)

Name: Mouse Anti-SAMD4A Recombinant Antibody (CBXS-2672)
SKU: CBMAB-S5424-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-2672

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa161-270 from SAMD4A (NP_056404) with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

sterile alpha motif domain containing 4A

Introduction

Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).

Entrez Gene ID

23034

UniProt ID

Q9UPU9

Alternative Names

Sterile Alpha Motif Domain Containing 4A; SAM Domain-Containing Protein 4A; SMAUG1; SAMD4; Sterile Alpha Motif Domain-Containing Protein 4A; Sterile Alpha Motif Domain Containing 4; Smaug Homolog (Drosophila); Protein Smaug Homolog 1;

Function

Acts as a translational repressor of SRE-containing messengers.

Biological Process

Biological Process nuclear-transcribed mRNA poly(A) tail shorteningManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of translationManual Assertion Based On ExperimentIDA:MGI

Cellular Location

Cytoplasm
Cell projection, dendrite
Synapse, synaptosome
Enriched in synaptoneurosomes (By similarity).
Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-SAMD4A Recombinant Antibody (1A4) (CAT#: CBMAB-A7887-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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