Mouse Anti-SAMM50 Recombinant Antibody (2A9) (CBMAB-A7888-LY)

Name: Mouse Anti-SAMM50 Recombinant Antibody (2A9)
SKU: CBMAB-A7888-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2A9

Application

WB, ELISA

Immunogen

SAMM50 (AAH07830, 1 a.a. ~ 468 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

sorting and assembly machinery component 50 homolog (S. cerevisiae)

Introduction

SAMM50 is a component of the sorting and assembly machinery (SAM) complex of the outer mitochondrial membrane. The SAM complex has a role in integrating beta-barrel proteins into the outer mitochondrial membrane (Humphries et al., 2005 [PubMed 15644312]).[supplied by OMIM

Entrez Gene ID

25813

UniProt ID

Q9Y512

Alternative Names

CGI-51; OMP85; SAM50; TOB55; TRG-3; YNL026W

Function

Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes (PubMed:22252321, PubMed:25781180).
Required for the assembly of TOMM40 into the TOM complex (PubMed:15644312).

Biological Process

Biological Process cristae formationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process inner mitochondrial membrane organization1 PublicationIC:UniProtKB
Biological Process mitochondrial respiratory chain complex assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein insertion into mitochondrial outer membraneManual Assertion Based On ExperimentIDA:BHF-UCL

Cellular Location

Mitochondrion outer membrane
Cytoplasm
Mitochondrion

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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