Rabbit Anti-SAMM50 Recombinant Antibody (CBXS-1614) (CBMAB-S4463-CQ)

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Basic Information

Host Animal
Rabbit
Clone
CBXS-1614
Application
WB, IHC-P, FC
Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
sorting and assembly machinery component 50 homolog (S. cerevisiae)
Introduction
This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane.
Entrez Gene ID
Human25813
Mouse68653
Rat300111
UniProt ID
HumanQ9Y512
MouseQ8BGH2
RatQ6AXV4
Alternative Names
SAMM50 Sorting And Assembly Machinery Component; Transformation-Related Gene 3 Protein; SAM50; TRG-3; Sorting And Assembly Machinery Component 50 Homolog (S. Cerevisiae); Sorting And Assembly Machinery Component 50 Homolog;
Function
Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes (PubMed:22252321, PubMed:25781180).
Required for the assembly of TOMM40 into the TOM complex (PubMed:15644312).
Biological Process
Biological Process cristae formationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process inner mitochondrial membrane organization1 PublicationIC:UniProtKB
Biological Process mitochondrial respiratory chain complex assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein insertion into mitochondrial outer membraneManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Mitochondrion outer membrane
Cytoplasm
Mitochondrion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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