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Mouse Anti-SAR1A Recombinant Antibody (3G5) (CBMAB-A7893-LY)

The product is antibody recognizes SAR1A. The antibody 3G5 immunoassay techniques such as: WB, ELISA.
See all SAR1A antibodies
Published Data
Fig. 1 Different Sec16 isoforms interact differentially with COPII components.
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Fig. 2 Different Sec16 isoforms interact differentially with COPII components.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
3G5
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
SAR1A (AAH03658, 1 a.a. ~ 198 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SAR1 homolog A (S. cerevisiae)
Entrez Gene ID
56681
UniProt ID
Q9NR31
Alternative Names
SAR1; SARA1; Sara; masra2
Function
Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity).
Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
Biological Process
Biological Process COPII-coated vesicle cargo loadingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process membrane organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of protein exit from endoplasmic reticulumManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of COPII vesicle coatingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle organizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endoplasmic reticulum
Golgi apparatus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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