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Mouse Anti-SAR1A Recombinant Antibody (CBXS-0122) (CBMAB-S3114-CQ)

This product is a mouse antibody that recognizes SAR1A. The antibody CBXS-0122 can be used for immunoassay techniques such as: ELISA, WB.
See all SAR1A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0122
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
SAR1A (AAH03658, 1 a.a.-198 a.a) Full length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SAR1 homolog A (S. cerevisiae)
Introduction
SAR1A (Secretion Associated Ras Related GTPase 1A) is a Protein Coding gene. Among its related pathways are TGF-Beta Pathway and Delta508-CFTR traffic / ER-to-Golgi in CF. Gene Ontology (GO) annotations related to this gene include GTP binding and signal transducer activity. An important paralog of this gene is SAR1B.
Entrez Gene ID
56681
UniProt ID
Q9NR31
Alternative Names
Secretion Associated Ras Related GTPase 1A; COPII-Associated Small GTPase; SARA1; SAR1; Sara; Secretion Associated, Ras Related GTPase 1A; SAR1a Gene Homolog (S. Cerevisiae) 1; SAR1a Gene Homolog 1 (S. Cerevisiae);
Function
Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity).
Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
Biological Process
Biological Process COPII-coated vesicle cargo loadingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process membrane organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of protein exit from endoplasmic reticulumManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of COPII vesicle coatingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle organizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endoplasmic reticulum
Golgi apparatus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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