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Mouse Anti-SCG2 Recombinant Antibody (CBXS-0136) (CBMAB-S3127-CQ)

This product is a mouse antibody that recognizes SCG2. The antibody CBXS-0136 can be used for immunoassay techniques such as: WB, ICC, IHC-P, IHC-Fr, ELISA.
See all SCG2 antibodies

Summary

Host Animal
Mouse
Specificity
Rat
Clone
CBXS-0136
Application
WB, ICC, IHC-P, IHC-Fr, ELISA

Basic Information

Immunogen
Chromogranin B
Specificity
Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 50% glycerol
Preservative
0.02% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
secretogranin II (chromogranin C)
Introduction
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
Entrez Gene ID
24765
UniProt ID
P10362
Alternative Names
Chcg
Function
Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
Biological Process
Biological Process angiogenesisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process endothelial cell migrationManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process eosinophil chemotaxisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process induction of positive chemotaxisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process inflammatory responseManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process MAPK cascadeManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process negative regulation of endothelial cell apoptotic processManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process negative regulation of endothelial cell proliferationManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process negative regulation of extrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive chemotaxisManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process protein secretionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
Neuroendocrine and endocrine secretory granules.
PTM
O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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