SCG2

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq]
Full Name
secretogranin II (chromogranin C)
Function
Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
Biological Process
Biological Process angiogenesisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process endothelial cell migrationManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process eosinophil chemotaxisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process induction of positive chemotaxisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process inflammatory responseManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process MAPK cascadeManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process negative regulation of endothelial cell apoptotic processManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process negative regulation of endothelial cell proliferationManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process negative regulation of extrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive chemotaxisManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process protein secretionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
Neuroendocrine and endocrine secretory granules.
PTM
O-glycosylated.
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Anti-SCG2 antibodies

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Human Recombinant SCG2 protein, His Tag (V2LY-0526-LY6697)

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Target: SCG2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-617
Tag: His Tag
Datasheet SDS

Mouse Anti-SCG2 Recombinant Antibody (6B7) (CBMAB-A7911-LY)

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Target: SCG2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6B7
Application*: E, E
Datasheet SDS

Recombinant Mouse Anti-SCG2 Recombinant Antibody (9G3/3) (CBMAB-XB1026-YC)

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Target: SCG2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Mouse, Rat
Clone: 9G3/3
Application*: F, IH, IP, WB
Datasheet SDS

Recombinant Mouse Anti-SCG2 Recombinant Antibody (6B1/3) (CBMAB-XB1025-YC)

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Target: SCG2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: 6B1/3
Application*: F, IH, IF, IP, WB
Datasheet SDS

Mouse Anti-SCG2 Recombinant Antibody (SGII 9G3/3) (CBMAB-S6559-CQ)

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Target: SCG2
Host: Mouse
Specificity: Rat
Clone: SGII 9G3/3
Application*: WB, IP, IF, F
Datasheet SDS

Mouse Anti-SCG2 Recombinant Antibody (CBXS-0136) (CBMAB-S3127-CQ)

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Target: SCG2
Host: Mouse
Specificity: Rat
Clone: CBXS-0136
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-SCG2 Recombinant Antibody (CBXS-5204) (CBMAB-S2421-CQ)

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Target: SCG2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-5204
Application*: E
Datasheet SDS

Mouse Anti-SCG2 Recombinant Antibody (SGII 6B1/3) (CBMAB-1795-CN)

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Target: SCG2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: SGII 6B1/3
Application*: F, IC, IF, C, P, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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