Rat Anti-SCGB3A2 Recombinant Antibody (381707) (CBMAB-C4235-CN)

Name: Rat Anti-SCGB3A2 Recombinant Antibody (381707)
SKU: CBMAB-C4235-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

381707

Application

Immunogen

E. coli-derived recombinant mouse UGRP1/SCGB3A2 isoform C, Leu22-Leu139, Accession # Q920H1

Specificity

Mouse

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS

More Infomation

Target

Full Name

secretoglobin, family 3A, member 2

Introduction

The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.[provided by RefSeq, Mar 2010]

Entrez Gene ID

117158

UniProt ID

Q920H1

Alternative Names

Secretoglobin Family 3A Member 2; Uteroglobin-Related Protein 1; Pneumo Secretory Protein 1; PnSP-1; PNSP1; UGRP1; Uteroglobin Related Protein 1; LU103;

Function

Secreted cytokine-like protein (PubMed:12847263).
Binds to the scavenger receptor MARCO (PubMed:12847263).
Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast (PubMed:12847263).
Strongly inhibits phospholipase A2 (PLA2G1B) activity (PubMed:24213919).
Seems to have anti-inflammatory effects in respiratory epithelium (By similarity).
Also has anti-fibrotic activity in lung (PubMed:24213919).
May play a role in fetal lung development and maturation (PubMed:24213919).
Promotes branching morphogenesis during early stages of lung development (PubMed:24213919).
In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (By similarity).

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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