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Rat Anti-SCGB3A2 Recombinant Antibody (381707) (CBMAB-C4235-CN)

This product is a Rat antibody that recognizes SCGB3A2. The antibody 381707 can be used for immunoassay techniques such as: WB.
See all SCGB3A2 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
381707
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
E. coli-derived recombinant mouse UGRP1/SCGB3A2 isoform C, Leu22-Leu139, Accession # Q920H1
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS

Target

Full Name
secretoglobin, family 3A, member 2
Introduction
The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.[provided by RefSeq, Mar 2010]
Entrez Gene ID
117158
UniProt ID
Q920H1
Alternative Names
Secretoglobin Family 3A Member 2; Uteroglobin-Related Protein 1; Pneumo Secretory Protein 1; PnSP-1; PNSP1; UGRP1; Uteroglobin Related Protein 1; LU103;
Function
Secreted cytokine-like protein (PubMed:12847263).
Binds to the scavenger receptor MARCO (PubMed:12847263).
Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast (PubMed:12847263).
Strongly inhibits phospholipase A2 (PLA2G1B) activity (PubMed:24213919).
Seems to have anti-inflammatory effects in respiratory epithelium (By similarity).
Also has anti-fibrotic activity in lung (PubMed:24213919).
May play a role in fetal lung development and maturation (PubMed:24213919).
Promotes branching morphogenesis during early stages of lung development (PubMed:24213919).
In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (By similarity).
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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