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Rabbit Anti-SCGB3A2 Recombinant Antibody (CBXS-1281) (CBMAB-S4140-CQ)

This product is a rabbit antibody that recognizes SCGB3A2. The antibody CBXS-1281 can be used for immunoassay techniques such as: WB, IF.
See all SCGB3A2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXS-1281
Antibody Isotype
IgG
Application
WB, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
secretoglobin, family 3A, member 2
Introduction
The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.
Entrez Gene ID
117156
UniProt ID
Q96PL1
Alternative Names
Secretoglobin Family 3A Member 2; Uteroglobin-Related Protein 1; Pneumo Secretory Protein 1; PnSP-1; PNSP1; UGRP1; Uteroglobin Related Protein 1; LU103;
Function
Secreted cytokine-like protein (PubMed:12847263).
Binds to the scavenger receptor MARCO (PubMed:12847263).
Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast (PubMed:12847263).
Strongly inhibits phospholipase A2 (PLA2G1B) activity (PubMed:24213919).
Seems to have anti-inflammatory effects in respiratory epithelium (By similarity).
Also has anti-fibrotic activity in lung (PubMed:24213919).
May play a role in fetal lung development and maturation (PubMed:24213919).
Promotes branching morphogenesis during early stages of lung development (PubMed:24213919).
In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (By similarity).
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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