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Mouse Anti-Sell Recombinant Antibody (IVA94) (CBMAB-L2726-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Selectin Lymphocyte (Sell). The antibody can be used for immunoassay techniques, such as FC.
See all Sell antibodies

Summary

Host Animal
Mouse
Specificity
Cattle
Clone
IVA94
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
Bovine leukocytes.
Specificity
Cattle
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Selectin L
Introduction
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. It mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. It promotes initial tethering and rolling of leukocytes in endothelia (By similarity).
Entrez Gene ID
281485
UniProt ID
P98131
Alternative Names
L-selectin; CD62 antigen-like family member L; LAM-1; LECAM1; leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 1; lymph node homing receptor; lymphocyte adhesion molecule 1; selectin L (lymphocyte adhesion molecule 1)
Function
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641).
Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641).
Biological Process
Biological Process calcium-dependent cell-cell adhesion via plasma membrane cell adhesion moleculesManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process leukocyte cell-cell adhesionManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process leukocyte tethering or rollingManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 39-332
Helical: 333-355
Cytoplasmic: 356-372
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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