Rat Anti-SEMA4C Recombinant Antibody (CBXS-1876) (CBMAB-S0131-CQ)

Name: Rat Anti-SEMA4C Recombinant Antibody (CBXS-1876)
SKU: CBMAB-S0131-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

CBXS-1876

Application

Immunogen

NS0-derived recombinant mouse Semaphorin 4C, Glu22-Gly664, Accession # Q64151

Specificity

Mouse

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

A saline solution, BSA

Preservative

Sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Semaphorin 4C

Introduction

SEMA4C (Succinate Dehydrogenase Complex Subunit D Pseudogene 5) is a Pseudogene.

Entrez Gene ID

20353

UniProt ID

Q64151

Alternative Names

AI426163; M-Sema F; Semacl1; Semaf; Semai; sema I

Function

Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity).
Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

Biological Process

Biological Process axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell migration in hindbrainISS:UniProtKB
Biological Process cerebellum developmentIEA:Ensembl
Biological Process muscle cell differentiationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of axon extension involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neural crest cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neural tube closureISS:UniProtKB
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of stress-activated MAPK cascadeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process semaphorin-plexin signaling pathwayISS:UniProtKB

Cellular Location

Postsynaptic density membrane
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane

Topology

Extracellular: 21-663
Helical: 664-684
Cytoplasmic: 685-833

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-SEMA4C Recombinant Antibody (CBXS-1875) (CAT#: CBMAB-S4671-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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